miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2

microRNAs (miRNAs) are small noncoding RNAs that regulate genes and contribute to many kinds of human diseases, including cancer. Two miRNAs, miR-511 and miR-1297, were investigated for a possible role in adenocarcinoma based on predicted binding sites for the TRIB2 oncogene by microRNA analysis sof...

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Veröffentlicht in:	PloS one 2012-10, Vol.7 (10), p.e46090-e46090
Hauptverfasser:	Zhang, Chao, Chi, Yong Liang, Wang, Ping Yu, Wang, Ya Qi, Zhang, Yan Xia, Deng, Jingti, Lv, Chang Jun, Xie, Shu Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Adenocarcinoma Adenocarcinoma - genetics Adenocarcinoma - pathology Analysis Animals Annexin V Apoptosis Base Sequence Binding sites Biochemistry Biology Blotting, Western Calcium-Calmodulin-Dependent Protein Kinases Cancer genetics CCAAT/enhancer-binding protein Cell growth Cell Line, Tumor Cell Proliferation Cytometry DNA Primers Flow Cytometry Fluorescence Fluorescence microscopy Genes Genetic aspects Green fluorescent protein Green Fluorescent Proteins - genetics Humans Immunohistochemistry In vivo methods and tests Intracellular Signaling Peptides and Proteins - genetics Kinases Laboratories Leukemia Lung cancer Lung Neoplasms - genetics Lung Neoplasms - pathology Medicine Mice Mice, Inbred BALB C Mice, Nude MicroRNA MicroRNAs MicroRNAs - physiology Microscopy, Fluorescence miRNA Molecular biology Oncogenes Polymerase Chain Reaction Prostate cancer Protein binding Proteins Ribonucleic acid RNA Tumor suppressor genes Tumorigenesis Western blotting Yang, Cindy
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