Myocilin polymorphisms and primary open-angle glaucoma: a systematic review and meta-analysis

Glaucoma is the leading cause of irreversible blindness in the world. Recent evidence indicates a role for genetic susceptibility to primary open-angle glaucoma (POAG). The relation between myocilin polymorphisms and POAG susceptibility has been studied in different populations. A meta-analysis of 3...

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Veröffentlicht in:	PloS one 2012-09, Vol.7 (9), p.e46632
Hauptverfasser:	Cheng, Jin-Wei, Cheng, Shi-Wei, Ma, Xiao-Ye, Cai, Ji-Ping, Li, You, Lu, Guo-Cai, Wei, Rui-Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Analysis Asian people Asians Biology Blindness Case-Control Studies Cytoskeletal Proteins - genetics Disease susceptibility Ethnicity Eye Proteins - genetics Genes Genetic aspects Genetic Association Studies Genetic polymorphisms Genetic Predisposition to Disease Glaucoma Glaucoma, Open-Angle - genetics Glycoproteins - genetics Humans Medicine Meta-analysis Minority & ethnic groups Mutation Odds Ratio Open-angle glaucoma Physiological aspects Polymorphism, Genetic Population studies Regression analysis Risk factors Studies Systematic review
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