The CTX-M-15-producing Escherichia coli clone O25b: H4-ST131 has high intestine colonization and urinary tract infection abilities

Increasing numbers of pyelonephritis-associated uropathogenic Escherichia coli (UPEC) are exhibiting high resistance to antibiotic therapy. They include a particular clonal group, the CTX-M-15-producing O25b:H4-ST131 clone, which has been shown to have a high dissemination potential. Here we show th...

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Veröffentlicht in:	PloS one 2012-09, Vol.7 (9), p.e46547-e46547
Hauptverfasser:	Vimont, Sophie, Boyd, Anders, Bleibtreu, Alexandre, Bens, Marcelle, Goujon, Jean-Michel, Garry, Louis, Clermont, Olivier, Denamur, Erick, Arlet, Guillaume, Vandewalle, Alain
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics Bacteria Bacterial infections beta-Lactam Resistance beta-Lactamases - biosynthesis Biofilms Biology Bladder Care and treatment Chemokines Cloning Colonization Cytokines Cytokines - genetics Cytokines - metabolism Dosage and administration E coli Enzymes Escherichia coli Escherichia coli Infections - microbiology Escherichia coli Proteins - biosynthesis Female Gene Expression Growth rate High resistance Humans Inflammation Inflammatory response Inoculation Intestine Intestines - microbiology Kidney - immunology Kidney - metabolism Kidney - microbiology Kidney Diseases - immunology Kidney Diseases - microbiology Kidney Diseases - pathology Kidneys Leukocytes (neutrophilic) Leukocytes (polymorphonuclear) Life Sciences Male Medicine Mice Mice, Inbred C3H Microbiota Nosocomial infections Pharmaceutical sciences Phylogenetics Phylogeny Plasmids Pyelonephritis Strains (organisms) Streptomycin Urinary bladder Urinary tract Urinary tract diseases Urinary tract infections Urinary Tract Infections - microbiology Urine Urogenital system Uropathogenic Escherichia coli - enzymology Uropathogenic Escherichia coli - growth & development Uropathogenic Escherichia coli - pathogenicity
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