Uterine NK cells are critical in shaping DC immunogenic functions compatible with pregnancy progression

Dendritic cell (DC) and natural killer (NK) cell interactions are important for the regulation of innate and adaptive immunity, but their relevance during early pregnancy remains elusive. Using two different strategies to manipulate the frequency of NK cells and DC during gestation, we investigated...

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Veröffentlicht in:	PloS one 2012-10, Vol.7 (10), p.e46755-e46755
Hauptverfasser:	Tirado-González, Irene, González, Irene Tirado, Barrientos, Gabriela, Freitag, Nancy, Otto, Teresa, Thijssen, Victor L J L, Moschansky, Petra, von Kwiatkowski, Petra, Klapp, Burghard F, Winterhager, Elke, Bauersachs, Stefan, Blois, Sandra M
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion Adaptive immunity Angiogenesis Animals Biology Cell activation Cell growth Cell interactions Cell proliferation Decidua Dendritic cells Dendritic Cells - cytology Dendritic Cells - immunology Dendritic Cells - metabolism Dermatology Enzyme-Linked Immunosorbent Assay Female Gene expression Gestation Immune response Immunity Immunogenicity Immunohistochemistry Implantation Internal medicine Killer cells Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Kinases Laboratory animals Male Medicine Mice Molecular biology Natural killer cells Oligonucleotide Array Sequence Analysis Preeclampsia Pregnancy Pregnant women Reproductive health Reverse Transcriptase Polymerase Chain Reaction Stromal cells Uterus Uterus - cytology Uterus - immunology Uterus - metabolism
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