Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2

Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae are major bacterial agents of meningitis. They each bind the 37/67-kDa laminin receptor (LamR) via the surface protein adhesins: meningococcal PilQ and PorA, H. influenzae OmpP2 and pneumococcal CbpA. We have previously repo...

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Veröffentlicht in:	PloS one 2012-09, Vol.7 (9), p.e46233-e46233
Hauptverfasser:	Abouseada, Noha M, Assafi, Mahde Saleh A, Mahdavi, Jafar, Oldfield, Neil J, Wheldon, Lee M, Wooldridge, Karl G, Ala'Aldeen, Dlawer A A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins Amino acids Antigens Bacteria Bacterial Proteins - chemistry Bacterial Proteins - metabolism Binding Biology Encephalitis Haemophilus influenzae Hemophilus infections Immunology Kinases Laminin Ligands Medicine Meningitis Neisseria meningitidis Peptides Porins - chemistry Porins - metabolism Protein Binding Protein Structure, Tertiary Proteins Receptors, Laminin - metabolism Risk factors Streptococcus infections Streptococcus pneumoniae Synthetic peptides Vaccines
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