Rapid intraspecific evolution of miRNA and siRNA genes in the mosquito Aedes aegypti

RNA silencing, or RNA interference (RNAi) in metazoans mediates development, reduces viral infection and limits transposon mobility. RNA silencing involves 21-30 nucleotide RNAs classified into microRNA (miRNA), exogenous and endogenous small interfering RNAs (siRNA), and Piwi-interacting RNA (piRNA...

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Veröffentlicht in:	PloS one 2012-09, Vol.7 (9), p.e44198
Hauptverfasser:	Bernhardt, Scott A, Simmons, Mark P, Olson, Ken E, Beaty, Barry J, Blair, Carol D, Black, William C
Format:	Artikel
Sprache:	eng
Schlagworte:	Aedes - genetics Aedes - metabolism Aedes aegypti Aedes albopictus Amino acids Animals Aquatic insects Biological evolution Biology Culex pipiens Culicidae Dengue Dengue fever Diversity indices Drosophila Drosophila melanogaster Evolution Evolution, Molecular Evolutionary genetics Exons Gene expression Gene Order Gene sequencing Genes Genetic Association Studies Genetic diversity Genetic Variation Genomes Immunity Immunology Infections Insect Proteins - chemistry Insect Proteins - genetics Insect Proteins - metabolism Insects Medicine MicroRNAs MicroRNAs - genetics miRNA Molecular evolution Mosquitoes Mutagenesis Pathology Phenotype Phylogeny Polymerase chain reaction Population genetics Positive selection Protein Interaction Domains and Motifs Proteins Ribonucleic acid RNA RNA polymerase RNA viruses RNA, Small Interfering - genetics RNA-mediated interference Selection, Genetic siRNA Thermal resistance Vector-borne diseases Viral diseases Viral infections Virology Viruses West Nile virus
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