Mac-2 binding protein is a novel E-selectin ligand expressed by breast cancer cells

Hematogenous metastasis involves the adhesion of circulating tumor cells to vascular endothelium of the secondary site. We hypothesized that breast cancer cell adhesion is mediated by interaction of endothelial E-selectin with its glycoprotein counter-receptor(s) expressed on breast cancer cells. At...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2012-09, Vol.7 (9), p.e44529-e44529
Hauptverfasser:	Shirure, Venktesh S, Reynolds, Nathan M, Burdick, Monica M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Adhesion tests Analysis Antigens Antigens, Neoplasm - metabolism Base Sequence Biology Blotting, Western Breast cancer Breast carcinoma Breast Neoplasms - metabolism Breast Neoplasms - pathology Cancer Cancer cells Cancer metastasis Cell Adhesion Cell adhesion & migration Cell Line, Tumor Colorectal cancer Cytometry E-selectin E-Selectin - metabolism Endothelial cells Endothelium Engineering schools Epitopes Female Flow Flow chambers Flow Cytometry Fluorescence Fluorescence microscopy Gene expression Glycoproteins Humans Immunoglobulins Immunoprecipitation Invasiveness Ligands Mass spectrometry Mass spectroscopy Medical prognosis Medical research Medicine Membrane Glycoproteins - metabolism Metastases Metastasis Microscopy Microscopy, Fluorescence Monoclonal antibodies Parallel plate flow cells Pathology Penicillin Protein binding Proteins RNA Interference Shear rate Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Therapeutic applications Tumor cell lines Tumor cells Tumors Umbilical vein Wall shear rate Western blotting
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!