PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow

Carnitine homeostasis is disrupted in lambs with endothelial dysfunction secondary to increased pulmonary blood flow (Shunt). Our recent studies have also indicated that the disruption in carnitine homeostasis correlates with a decrease in PPAR-γ expression in Shunt lambs. Thus, this study was carri...

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Veröffentlicht in:PloS one 2012-09, Vol.7 (9), p.e41555
Hauptverfasser: Sharma, Shruti, Sun, Xutong, Rafikov, Ruslan, Kumar, Sanjiv, Hou, Yali, Oishi, Peter E, Datar, Sanjeev A, Raff, Gary, Fineman, Jeffrey R, Black, Stephen M
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Sprache:eng
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