Specific expression of channelrhodopsin-2 in single neurons of Caenorhabditis elegans

Optogenetic approaches using light-activated proteins like Channelrhodopsin-2 (ChR2) enable investigating the function of populations of neurons in live Caenorhabditis elegans (and other) animals, as ChR2 expression can be targeted to these cells using specific promoters. Sub-populations of these ne...

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Veröffentlicht in:	PloS one 2012-08, Vol.7 (8), p.e43164-e43164
Hauptverfasser:	Schmitt, Cornelia, Schultheis, Christian, Pokala, Navin, Husson, Steven J, Liewald, Jana F, Bargmann, Cornelia I, Gottschalk, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal Biochemistry Biology Caenorhabditis elegans Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - biosynthesis Caenorhabditis elegans Proteins - genetics Deoxyribonucleic acid DNA Gene Expression Profiling Gene Expression Regulation Green Fluorescent Proteins - metabolism Illumination Life sciences Light Microscopy, Fluorescence - methods Models, Biological Models, Genetic Nematodes Nervous system Neurons Neurons - metabolism Plasmids - metabolism Populations Promoter Regions, Genetic Promoters Proteins Recombinase Recombinases - metabolism Rhodopsin - biosynthesis Rhodopsin - genetics Rodents Sensory neurons Stem cells Transgenes Worms
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