Clostridium difficile spore-macrophage interactions: spore survival

Clostridium difficile is the main cause of nosocomial infections including antibiotic associated diarrhea, pseudomembranous colitis and toxic megacolon. During the course of Clostridium difficile infections (CDI), C. difficile undergoes sporulation and releases spores to the colonic environment. The...

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Veröffentlicht in:	PloS one 2012-08, Vol.7 (8), p.e43635
Hauptverfasser:	Paredes-Sabja, Daniel, Cofre-Araneda, Glenda, Brito-Silva, Christian, Pizarro-Guajardo, Marjorie, Sarker, Mahfuzur R
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Amino acids Animals Antibiotics Bacillus anthracis Bacteria Bacterial spores Biology Cell death Cell Line Cell Survival Clostridium difficile Clostridium difficile - physiology Clostridium perfringens Colitis Cytotoxicity Diarrhea Electron micrographs Electron microscopy Fluorescence Fluorescence microscopy Genetic aspects Health aspects Hospitals Host-Pathogen Interactions Immune system Infections Innate immunity Macrophages Macrophages - cytology Macrophages - microbiology Medicine Mice Micrography Microscopy Nosocomial infection Nuclei Nuclei (cytology) Phagocytosis Phagosomes - microbiology Physiological aspects Polymerization Proteins Pseudomembranous colitis Sonication Spores Spores, Bacterial - physiology Sporulation
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