Increased transmission of Mycobacterium tuberculosis Beijing genotype strains associated with resistance to streptomycin: a population-based study

Studies have shown that the Mycobacterium tuberculosis Beijing genotype is an emerging pathogen that is frequently associated with drug resistance. This suggests that drug resistant Beijing strains have a relatively high transmission fitness compared to other drug-resistant strains. We studied the r...

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Veröffentlicht in:	PloS one 2012-08, Vol.7 (8), p.e42323-e42323
Hauptverfasser:	Buu, Tran N, van Soolingen, Dick, Huyen, Mai N T, Lan, Nguyen T N, Quy, Hoang T, Tiemersma, Edine W, Kremer, Kristin, Borgdorff, Martien W, Cobelens, Frank G J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult Aged AIDS Analysis Antitubercular agents Biology Cluster Analysis Clustering Deoxyribonucleic acid Disease transmission DNA DNA Fingerprinting DNA, Bacterial - analysis DNA, Bacterial - genetics Drug resistance Drug Resistance, Bacterial - drug effects Drug Resistance, Bacterial - genetics Drug Resistance, Multiple - drug effects Drug Resistance, Multiple - genetics Female Fitness Genetic aspects Genotype Genotype & phenotype Genotypes HIV Hospitals Human immunodeficiency virus Humans Infectious diseases Laboratories Male Medical research Medicine Microbial drug resistance Middle Aged Multidrug resistance Multidrug resistant organisms Mutation Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - physiology Patient compliance Patients Population Population studies Population-based studies Risk Factors Rural areas Rural Population - statistics & numerical data Smear Strains (organisms) Streptomycin Streptomycin - pharmacology Studies Tuberculosis Tuberculosis, Pulmonary - transmission Young Adult
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