Genome-wide detection of spontaneous chromosomal rearrangements in bacteria

Genome rearrangements have important effects on bacterial phenotypes and influence the evolution of bacterial genomes. Conventional strategies for characterizing rearrangements in bacterial genomes rely on comparisons of sequenced genomes from related species. However, the spectra of spontaneous rea...

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Veröffentlicht in:	PloS one 2012-08, Vol.7 (8), p.e42639
Hauptverfasser:	Sun, Song, Ke, Rongqin, Hughes, Diarmaid, Nilsson, Mats, Andersson, Dan I
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Bacteria Biochemistry Biology Chromosome rearrangements Chromosomes Chromosomes, Bacterial - genetics Clonal deletion Computer applications Deoxyribonucleic acid DNA E coli Escherichia coli Feasibility studies Gene expression Gene mapping Gene Rearrangement - genetics Gene sequencing Genes, Bacterial - genetics Genetic aspects Genetics Genome, Bacterial - genetics Genomes Genomics Homology Hybridization Immunology Inversions Molecular Sequence Data Mutation Population Populations Reproducibility of Results Reproduction (copying) Salmonella Salmonella enterica Salmonella enterica - genetics Sequence Analysis, DNA Sequence Deletion - genetics
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