Androgen-responsive microRNAs in mouse Sertoli cells

Although decades of research have established that androgen is essential for spermatogenesis, androgen's mechanism of action remains elusive. This is in part because only a few androgen-responsive genes have been definitively identified in the testis. Here, we propose that microRNAs--small, non...

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Veröffentlicht in:	PloS one 2012-07, Vol.7 (7), p.e41146
Hauptverfasser:	Panneerdoss, Subbarayalu, Chang, Yao-Fu, Buddavarapu, Kalyan C, Chen, Hung-I Harry, Shetty, Gunapala, Wang, Huizhen, Chen, Yidong, Kumar, T Rajendra, Rao, Manjeet K
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen receptors Androgens Androgens - pharmacology Animals Base Sequence Biology Cluster Analysis Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Gene expression Gene Expression Profiling Gene Expression Regulation - drug effects Genes Hormone replacement therapy Infertility Kinases Male Medical research Meiosis Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Mice MicroRNA MicroRNAs - genetics miRNA Organ Specificity - genetics Ribonucleic acid RNA Rodents Sertoli cells Sertoli Cells - drug effects Sertoli Cells - metabolism Signaling Spermatogenesis Spermatogenesis - drug effects Spermatogenesis - genetics Testis - metabolism Testosterone - pharmacology Transcription Factors - genetics Transcription Factors - metabolism
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