Advanced methylome analysis after bisulfite deep sequencing: an example in Arabidopsis

Deep sequencing after bisulfite conversion (BS-Seq) is the method of choice to generate whole genome maps of cytosine methylation at single base-pair resolution. Its application to genomic DNA of Arabidopsis flower bud tissue resulted in the first complete methylome, determining a methylation rate o...

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Veröffentlicht in:	PloS one 2012-07, Vol.7 (7), p.e41528-e41528
Hauptverfasser:	Dinh, Huy Q, Dubin, Manu, Sedlazeck, Fritz J, Lettner, Nicole, Mittelsten Scheid, Ortrun, von Haeseler, Arndt
Format:	Artikel
Sprache:	eng
Schlagworte:	Arabidopsis Arabidopsis - genetics Arabidopsis thaliana Base Sequence Bioinformatics Biology Bisulfite Computer Science Conversion Cytosine Cytosine - metabolism Data processing Deoxyribonucleic acid DNA DNA methylation DNA Methylation - genetics Epigenetics Gene expression Gene mapping Gene sequencing Genome, Plant - genetics Genomes Genomics High-Throughput Nucleotide Sequencing - methods Laboratories Methods Methylation Perutz, Max Plant biology Pyrimidines Reference Standards Reproducibility of Results Sequence Alignment Sequence Analysis, DNA Software packages Sulfites Sulfites - chemistry
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