Prediction of metal ion-binding sites in proteins using the fragment transformation method

The structure of a protein determines its function and its interactions with other factors. Regions of proteins that interact with ligands, substrates, and/or other proteins, tend to be conserved both in sequence and structure, and the residues involved are usually in close spatial proximity. More t...

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Veröffentlicht in:	PloS one 2012-06, Vol.7 (6), p.e39252
Hauptverfasser:	Lu, Chih-Hao, Lin, Yu-Feng, Lin, Jau-Ji, Yu, Chin-Sheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - chemistry Analysis Banks (Finance) Binding Sites Biochemistry Bioinformatics Biology Calcium Computer applications Conserved sequence Copper Corynebacterium E coli Enzymes Identification methods Informatics Ions Ions - chemistry Iron Magnesium Metal ions Metalloproteins - chemistry Metals Metals - chemistry Methods Models, Molecular Neural networks Peptides - chemistry Phormidium laminosum Physics Protein Binding Protein Conformation Protein structure Proteins Residues Ribonucleotide reductase ROC Curve Substrates Transformation Transformations (mathematics) Zinc
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