Optimised anaesthesia to reduce post operative cognitive decline (POCD) in older patients undergoing elective surgery, a randomised controlled trial

The study determined the one year incidence of post operative cognitive decline (POCD) and evaluated the effectiveness of an intra-operative anaesthetic intervention in reducing post-operative cognitive impairment in older adults (over 60 years of age) undergoing elective orthopaedic or abdominal su...

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Veröffentlicht in:	PloS one 2012-06, Vol.7 (6), p.e37410-e37410
Hauptverfasser:	Ballard, Clive, Jones, Emma, Gauge, Nathan, Aarsland, Dag, Nilsen, Odd Bjarte, Saxby, Brian K, Lowery, David, Corbett, Anne, Wesnes, Keith, Katsaiti, Eirini, Arden, James, Amoako, Derek, Amaoko, Derek, Prophet, Nicholas, Purushothaman, Balaji, Green, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Age Aged Aged, 80 and over Analysis Anesthesia Anesthesiology Biology Brain research Clinical trials Cognition Disorders - etiology Cognition Disorders - prevention & control Cognitive ability Cohort analysis Cytokines Data analysis Data processing Elderly patients Elective surgery Elective Surgical Procedures Executive function Heart surgery Hospitals Humans Hypoxia Impairment Intervention Longitudinal Studies Medical research Medicine Monitoring Neurosciences Neurotoxicity Older people Oxygen Oxygen content Oxygenation Patients Phosphorylation Postoperative Complications Prospective Studies Proteins Randomization Reaction time Saturation Surgery Traumatic brain injury Vigilance
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