Functional characterizations of RIG-I to GCRV and viral/bacterial PAMPs in grass carp Ctenopharyngodon idella

RIG-I (retinoic acid inducible gene-I) is one of the key cytosolic pattern recognition receptors (PRRs) for detecting nucleotide pathogen associated molecular patterns (PAMPs) and mediating the induction of type I interferon and inflammatory cytokines in innate immune response. Though the mechanism...

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Veröffentlicht in:	PloS one 2012-07, Vol.7 (7), p.e42182-e42182
Hauptverfasser:	Chen, Lijun, Su, Jianguo, Yang, Chunrong, Peng, Limin, Wan, Quanyuan, Wang, Lan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral activity Bacteria Biological response modifiers Biology Carp Carps Carps - genetics Carps - microbiology Carps - virology Caspase Cell lines Cellular signal transduction Ctenopharyngodon idella Cytokines DNA helicase Double-stranded RNA Fish Fishes Immune response Immune system Inflammation Innate immunity Interferon Kinases Lipopolysaccharides Medicine Molecular Sequence Data mRNA Pattern recognition Pattern recognition receptors Plasmids Polyinosinic:polycytidylic acid Polymerase chain reaction Proteins Real-Time Polymerase Chain Reaction Receptors Recombinant proteins Retinoic acid RNA Rodents Signal Transduction Signaling Stimulation Tretinoin Virus Diseases - metabolism Virus Diseases - virology Viruses Zebrafish
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