Association of polymorphism in pri-microRNAs-371-372-373 with the occurrence of hepatocellular carcinoma in hepatitis B virus infected patients

Micro RNAs-371-372-373 (miRNAs-371-373), originating from the same pri-miRNA transcript, are reported to be upregulated in hepatocellular carcinoma (HCC) and to be related to the regulation of hepatitis B virus (HBV) infection. Our study investigated whether pri-miRNAs-371-373 polymorphisms are asso...

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Veröffentlicht in:	PloS one 2012-07, Vol.7 (7), p.e41983
Hauptverfasser:	Kwak, Min-Sun, Lee, Dong Hyeon, Cho, Yuri, Cho, Eun-Ju, Lee, Jeong-Hoon, Yu, Su Jong, Yoon, Jung-Hwan, Lee, Hyo-Suk, Kim, Chung Yong, Cheong, Jae Youn, Cho, Sung Won, Shin, Hyoung Doo, Kim, Yoon Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens Biology Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - pathology Carcinoma, Hepatocellular - virology Carriers Cirrhosis Deoxyribonucleic acid Development and progression DNA DNA sequencing Female Gastroenterology Gene expression Gene Frequency Gene polymorphism Gene sequencing Genetic aspects Genetic diversity Genetic Predisposition to Disease - genetics Genotypes Haplotypes Haplotypes - genetics Health aspects Hepatitis Hepatitis B Hepatitis B virus Hepatitis B virus - metabolism Hepatitis B virus - pathogenicity Hepatocellular carcinoma Humans Infection Infections Internal medicine Laws, regulations and rules Liver Liver cancer Liver cirrhosis Liver Neoplasms - genetics Liver Neoplasms - pathology Liver Neoplasms - virology Male Medical imaging Medical research Medicine MicroRNA MicroRNAs MicroRNAs - genetics Middle Aged miRNA Nucleotide sequence Patients Physicians Polymorphism Polymorphism, Single Nucleotide Regression analysis Statistical analysis Transcription Viruses Young Adult
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