Sleep phenotyping in a mouse model of extreme trait anxiety

There is accumulating evidence that anxiety impairs sleep. However, due to high sleep variability in anxiety disorders, it has been difficult to state particular changes in sleep parameters caused by anxiety. Sleep profiling in an animal model with extremely high vs. low levels of trait anxiety migh...

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Veröffentlicht in:	PloS one 2012-07, Vol.7 (7), p.e40625-e40625
Hauptverfasser:	Jakubcakova, Vladimira, Flachskamm, Cornelia, Landgraf, Rainer, Kimura, Mayumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Analysis Animal models Animals Antidepressants Anxiety Anxiety Disorders - physiopathology Behavior Behavior disorders Biology Disease Models, Animal Electroencephalography Eye movements Homeostasis House mouse Laboratory animals Latency Latency Period (Psychology) Male Medicine Mental depression Mice NREM sleep Phenotype Phenotypes Phenotyping Psychiatry Psychopathology Quantitative Trait, Heritable Rapid eye movement state REM sleep Rodents Sleep Sleep (NREM) Sleep (REM) Sleep - physiology Sleep and wakefulness Sleep deprivation Sleep Deprivation - physiopathology Sleep disorders Sleep, REM - physiology Surgery Vigilance Wakefulness Wakefulness - physiology Young adults
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