Protective effect of curcumin on pulmonary and cardiovascular effects induced by repeated exposure to diesel exhaust particles in mice

Particulate air pollution has been associated with increased risk of cardiopulmonary diseases. However, the underlying mechanisms are not fully understood. We have previously demonstrated that single dose exposure to diesel exhaust particle (DEP) causes lung inflammation and peripheral thrombotic ev...

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Veröffentlicht in:	PloS one 2012-06, Vol.7 (6), p.e39554
Hauptverfasser:	Nemmar, Abderrahim, Subramaniyan, Deepa, Ali, Badreldin H
Format:	Artikel
Sprache:	eng
Schlagworte:	Air pollution Air pollution measurements Alveoli Animals Anti-inflammatory agents Atmospheric pollution Biology Blood pressure Blood Pressure - drug effects Bronchoalveolar Lavage Bronchus C-reactive protein C-Reactive Protein - metabolism Cardiovascular disease Coagulation Curcumin Curcumin - pharmacology Diesel Diesel emissions Diesel engines Earth Sciences Exposure Health risks Health sciences Heart failure Inflammation Lung - drug effects Lungs Macrophages Male Medicine Mice Physiology Plasminogen activator inhibitors Pollution abatement Polyamide-imides Pretreatment Respiratory tract Rodents Studies Thromboembolism Thrombosis Toxicity Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF Tumor necrosis factor-α Vehicle Emissions - toxicity
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