5-Methylcytosine and 5-hydroxymethylcytosine spatiotemporal profiles in the mouse zygote

In the mouse zygote, DNA methylation patterns are heavily modified, and differ between the maternal and paternal pronucleus. Demethylation of the paternal genome has been described as an active and replication-independent process, although the mechanisms responsible for it remain elusive. Recently,...

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Veröffentlicht in:PloS one 2012-05, Vol.7 (5), p.e38156-e38156
Hauptverfasser: Salvaing, Juliette, Aguirre-Lavin, Tiphaine, Boulesteix, Claire, Lehmann, Gaëtan, Debey, Pascale, Beaujean, Nathalie
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Sprache:eng
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