Influence of prenatal arsenic exposure and newborn sex on global methylation of cord blood DNA

An emerging body of evidence indicates that early-life arsenic (As) exposure may influence the trajectory of health outcomes later in life. However, the mechanisms underlying these observations are unknown. The objective of this study was to investigate the influence of prenatal As exposure on globa...

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Veröffentlicht in:	PloS one 2012-05, Vol.7 (5), p.e37147
Hauptverfasser:	Pilsner, J Richard, Hall, Megan N, Liu, Xinhua, Ilievski, Vesna, Slavkovich, Vesna, Levy, Diane, Factor-Litvak, Pam, Yunus, Mahammad, Rahman, Mahfuzar, Graziano, Joseph H, Gamble, Mary V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alu Elements Analysis Aquifers Arsenic Arsenic - toxicity Assaying Biology Biomarkers Blood Blood Cells - metabolism Cancer Cord blood Creatinine Deoxyribonucleic acid Disease DNA DNA methylation DNA Methylation - drug effects Drinking water Environmental health Enzymes Epidemiology Epigenetic inheritance Epigenetics Exposure Female Fetal Blood Gender aspects Gene expression Genetic research Genomes Health sciences Humans Infant, Newborn Inuit Long Interspersed Nucleotide Elements Male Maternal Exposure Medical research Medicine Metabolism Methylation Neonates Newborn babies Newborn infants Pregnancy Pregnant women Prenatal experience Prevention Public health Quartiles Regression analysis Sex Sex differences Sex Factors Studies Tumors Umbilical cord Womens health Young Adult
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