Daily rhythms of plasma melatonin, but not plasma leptin or leptin mRNA, vary between lean, obese and type 2 diabetic men

Melatonin and leptin exhibit daily rhythms that may contribute towards changes in metabolic physiology. It remains unclear, however, whether this rhythmicity is altered in obesity or type 2 diabetes (T2DM). We tested the hypothesis that 24-hour profiles of melatonin, leptin and leptin mRNA are alter...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2012-05, Vol.7 (5), p.e37123-e37123
Hauptverfasser:	Mäntele, Simone, Otway, Daniella T, Middleton, Benita, Bretschneider, Silvia, Wright, John, Robertson, M Denise, Skene, Debra J, Johnston, Jonathan D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Analysis Analysis of Variance Beverages Biological clocks Biology Circadian rhythm Circadian Rhythm - physiology Cloning Cortisol Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - physiopathology Diabetics Diet Diurnal DNA Primers - genetics Endocrinology Ethics Fasting Gene expression Gene Expression Profiling Glucocorticoids Glucose Humans Hypertension Insulin resistance Laboratories Leptin Leptin - blood Leptin - genetics Male Mammals Medicine Melatonin Melatonin - blood Messenger RNA Metabolism Middle Aged Nocturnal Obesity Obesity - blood Obesity - physiopathology Pharmacology Phodopus sungorus Physiological aspects Physiology Posture Radioimmunoassay RNA, Messenger - blood Rodents Sleep Sleep and wakefulness Studies Thinness - blood Thinness - physiopathology Type 2 diabetes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!