Anti-HIV-1 activity of a new scorpion venom peptide derivative Kn2-7

For over 30 years, HIV/AIDS has wreaked havoc in the world. In the absence of an effective vaccine for HIV, development of new anti-HIV agents is urgently needed. We previously identified the antiviral activities of the scorpion-venom-peptide-derived mucroporin-M1 for three RNA viruses (measles viru...

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Veröffentlicht in:	PloS one 2012-04, Vol.7 (4), p.e34947
Hauptverfasser:	Chen, Yaoqing, Cao, Luyang, Zhong, Maohua, Zhang, Yan, Han, Chen, Li, Qiaoli, Yang, Jingyi, Zhou, Dihan, Shi, Wei, He, Benxia, Liu, Fang, Yu, Jie, Sun, Ying, Cao, Yuan, Li, Yaoming, Li, Wenxin, Guo, Deying, Cao, Zhijian, Yan, Huimin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS AIDS vaccines Amino Acid Sequence Anti-HIV Agents - chemical synthesis Anti-HIV Agents - pharmacology Anti-HIV Agents - toxicity Antigens Antimicrobial agents Antimicrobial Cationic Peptides - chemical synthesis Antimicrobial Cationic Peptides - pharmacology Antimicrobial Cationic Peptides - toxicity Antiviral activity Antiviral agents Bacteria Biology Biosensors CCR5 protein Cell Line Chemokines Cloning CXCR4 protein Cytotoxicity Development and progression Disease transmission Dose-Response Relationship, Drug Drug Design Health aspects HIV HIV-1 - drug effects Human immunodeficiency virus Humans Infections Laboratories Life sciences Measles Medicine Molecular Sequence Data Peptides Protein Binding Protein Structure, Secondary Proteins Ribonucleic acid RNA RNA viruses Scorpion Venoms - chemical synthesis Scorpion Venoms - pharmacology Scorpion Venoms - toxicity Toxicity Venom Venoms Virology Viruses
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