Enhanced hippocampal long-term potentiation and fear memory in Btbd9 mutant mice

Polymorphisms in BTBD9 have recently been associated with higher risk of restless legs syndrome (RLS), a neurological disorder characterized by uncomfortable sensations in the legs at rest that are relieved by movement. The BTBD9 protein contains a BTB/POZ domain and a BACK domain, but its function...

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Veröffentlicht in:	PloS one 2012-04, Vol.7 (4), p.e35518
Hauptverfasser:	DeAndrade, Mark P, Zhang, Li, Doroodchi, Atbin, Yokoi, Fumiaki, Cheetham, Chad C, Chen, Huan-Xin, Roper, Steven N, Sweatt, J David, Li, Yuqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Animals beta-Galactosidase - biosynthesis beta-Galactosidase - genetics Biology Brain Carrier Proteins - genetics Carrier Proteins - metabolism Conditioning (Psychology) Drosophila melanogaster Dynamin Dynamin I - metabolism Embryonic stem cells Endocytosis Enzymes Excitatory Postsynaptic Potentials Fear Fear - physiology Fear - psychology Freezing Reaction, Cataleptic Gene expression Genes Genes, Reporter Genetic aspects Hippocampus Hippocampus - metabolism Hippocampus - physiology Homology Ischemia Laboratory animals Learning Legs Long-Term Potentiation Medicine Memory Mice Mice, Knockout Mutagenesis, Insertional Mutants Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Nervous system diseases Neurodegeneration Neurological disorders Neurology Neuronal Plasticity Neurosciences Neurosurgery Pain Physiology Plasticity Proteins Psychophysiology Restless legs syndrome Restless Legs Syndrome - metabolism Rodents Sensory perception Sleep Stem cells Studies Synapses Synaptic plasticity Synaptic transmission Synaptosomes - metabolism
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