Mutational analysis of the cyanobacterial nitrogen regulator PipX

PipX provides a functional link between the cyanobacterial global transcriptional regulator NtcA and the signal transduction protein P(II), a protein found in all three domains of life as integrators of signals of the nitrogen and carbon balance. PipX, which is toxic in the absence of P(II), can for...

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Veröffentlicht in:	PloS one 2012-04, Vol.7 (4), p.e35845
Hauptverfasser:	Laichoubi, Karim Boumediene, Espinosa, Javier, Castells, Miguel Angel, Contreras, Asunción
Format:	Artikel
Sprache:	eng
Schlagworte:	Active control Amino Acid Substitution Amino acids Anacystis nidulans Bacterial Proteins - genetics Bacterial Proteins - metabolism Binding Sites Biocompatibility Biology Carbon - metabolism Cellular signal transduction Cloning Cloning, Molecular Complex formation Cyanobacteria DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism DNA-directed RNA polymerase DNA-Directed RNA Polymerases - genetics DNA-Directed RNA Polymerases - metabolism E coli Escherichia coli Gene expression Gene Expression Regulation, Bacterial Gene mutation Genes Genetic aspects Genomics Integrators Ketoglutaric acid Ketoglutaric Acids - metabolism Kinases Laboratories Models, Molecular Molecular biology Mutagenesis Mutation Nitrogen Nitrogen - metabolism Phosphorylation PII Nitrogen Regulatory Proteins - genetics PII Nitrogen Regulatory Proteins - metabolism Plasmids Point Mutation Protein Binding Proteins Recombinant Proteins - genetics Recombinant Proteins - metabolism Ribonucleic acid RNA RNA polymerase Signal transduction Synechococcus Synechococcus - genetics Synechococcus - metabolism Toxicity Transcription Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic Transduction Two-Hybrid System Techniques Yeast
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