Absence of XMRV and closely related viruses in primary prostate cancer tissues used to derive the XMRV-infected cell line 22Rv1

The 22Rv1 cell line is widely used for prostate cancer research and other studies throughout the world. These cells were established from a human prostate tumor, CWR22, that was serially passaged in nude mice and selected for androgen independence. The 22Rv1 cells are known to produce high titers of...

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Veröffentlicht in:	PloS one 2012-05, Vol.7 (5), p.e36072-e36072
Hauptverfasser:	Das Gupta, Jaydip, Luk, Ka-Cheung, Tang, Ning, Gaughan, Christina, Klein, Eric A, Kandel, Eugene S, Hackett, Jr, John, Silverman, Robert H
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Animal tissues Base Sequence Biology Blood & organ donations Cancer Cell Line, Tumor Chronic fatigue syndrome Cytokines Deduction Deoxyribonucleic acid DNA DNA Primers DNA, Viral - genetics Ethanol Fluorescence Fluorescence in situ hybridization Genomes Genomics Humans In Situ Hybridization, Fluorescence Infections Laboratories Leukemia Male Mass spectrometry Medicine Mice Patients Polymerase chain reaction Polymorphism, Single Nucleotide Prostate cancer Prostatic Neoplasms - pathology Prostatic Neoplasms - virology Real-Time Polymerase Chain Reaction Scientific imaging Studies Viruses Working groups Xenografts Xenotropic Xenotropic murine leukemia virus-related virus - genetics Xenotropic murine leukemia virus-related virus - isolation & purification
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