The pseudokinase NIPI-4 is a novel regulator of antimicrobial peptide gene expression

Hosts have developed diverse mechanisms to counter the pathogens they face in their natural environment. Throughout the plant and animal kingdoms, the up-regulation of antimicrobial peptides is a common response to infection. In C. elegans, infection with the natural pathogen Drechmeria coniospora l...

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Veröffentlicht in:	PloS one 2012-03, Vol.7 (3), p.e33887-e33887
Hauptverfasser:	Labed, Sid Ahmed, Omi, Shizue, Gut, Martha, Ewbank, Jonathan J, Pujol, Nathalie
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Anti-Infective Agents - metabolism Antibiotics Antiinfectives and antibacterials Antimicrobial Cationic Peptides - genetics Antimicrobial Cationic Peptides - metabolism Antimicrobial peptides Ascomycota - physiology Biology Caenorhabditis elegans Caenorhabditis elegans - enzymology Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Command and control systems Epidermis Epidermis - enzymology Gene expression Gene Expression Regulation Genes Genetic screening Genetic testing Genomes Genomics GTP-Binding Protein alpha Subunits, G12-G13 - metabolism Health aspects Immunology Infections Innate immunity Kinases Laboratories Life Sciences Meloidogyne incognita Mutagenesis Mutants Nematodes Numerical controls Pathogens Peptides Protein kinase C Protein-Tyrosine Kinases - metabolism Proteins Roundworms Signal transduction Transcription factors Trends Up-Regulation Worms
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