African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts

The risk of type 2 diabetes is approximately 2-fold higher in African Americans than in European Americans even after adjusting for known environmental risk factors, including socioeconomic status (SES), suggesting that genetic factors may explain some of this population difference in disease risk....

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Veröffentlicht in:	PloS one 2012-03, Vol.7 (3), p.e32840
Hauptverfasser:	Cheng, Ching-Yu, Reich, David, Haiman, Christopher A, Tandon, Arti, Patterson, Nick, Selvin, Elizabeth, Elizabeth, Selvin, Akylbekova, Ermeg L, Brancati, Frederick L, Coresh, Josef, Boerwinkle, Eric, Altshuler, David, Taylor, Herman A, Henderson, Brian E, Wilson, James G, Kao, W H Linda
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult African Americans Aged Analysis Animals Arteriosclerosis Atherosclerosis Biology Black or African American - genetics Blood Body mass Body mass index Body size Censuses Chromosome 12 Cohort Studies Confidence intervals Cultural differences Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - genetics Disease prevention Education Environmental risk Epidemiology Ethnic factors Female Gene mapping Genetic aspects Genetic factors Genetic Markers Genetic Predisposition to Disease Genome-Wide Association Study Genomes Genomics Glucose Health care Health risks Heart Hemoglobin Humans Hypertension Loci Male Medical research Medical schools Medicine Middle Aged Minority & ethnic groups Multiple sclerosis Odds Ratio Population genetics Preventive medicine Prospective Studies Prostate cancer Public health Quantitative Trait, Heritable Risk analysis Risk Factors Socioeconomics Studies Type 2 diabetes United States White People - genetics Young Adult
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