Ribosomal history reveals origins of modern protein synthesis

The origin and evolution of the ribosome is central to our understanding of the cellular world. Most hypotheses posit that the ribosome originated in the peptidyl transferase center of the large ribosomal subunit. However, these proposals do not link protein synthesis to RNA recognition and do not u...

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Veröffentlicht in:	PloS one 2012-03, Vol.7 (3), p.e32776-e32776
Hauptverfasser:	Harish, Ajith, Caetano-Anollés, Gustavo
Format:	Artikel
Sprache:	eng
Schlagworte:	Accretion Acids Biologi Biological evolution Biological Sciences Biology Catalysis Catalytic RNA Censuses Chemical synthesis Classification Comparative analysis Deposition Evolution Evolution, Molecular Genomes Genomics Likelihood Functions Machinery Machinery and equipment Mediation Metabolism Models, Molecular Molecular biology Morphometry Natural Sciences Naturvetenskap Phylogenetics Phylogeny Protein biosynthesis Protein Biosynthesis - physiology Protein synthesis Proteins Proteins - chemistry Replicase Ribonucleic acid Ribonucleoproteins - genetics Ribonucleoproteins - metabolism Ribosomes - genetics Ribosomes - physiology Ribozymes RNA RNA, Ribosomal - chemistry RNA-directed RNA polymerase Studies Transcription
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