PTEN as a prognostic and predictive marker in postoperative radiotherapy for squamous cell cancer of the head and neck

Tumor suppressor PTEN is known to control a variety of processes related to cell survival, proliferation, and growth. PTEN expression is considered as a prognostic factor in some human neoplasms like breast, prostate, and thyroid cancer. In this study we analyzed the influence of PTEN expression on...

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Veröffentlicht in:	PloS one 2012-03, Vol.7 (3), p.e33396-e33396
Hauptverfasser:	Snietura, Miroslaw, Jaworska, Magdalena, Mlynarczyk-Liszka, Joanna, Goraj-Zajac, Aleksandra, Piglowski, Wojciech, Lange, Dariusz, Wozniak, Grzegorz, Nowara, Elzbieta, Suwinski, Rafal
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis Angiogenesis Biology Biomarkers, Tumor - metabolism Breast cancer Cancer Cancer therapies Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - radiotherapy Cell survival Chromosomes Colorectal cancer Combined Modality Therapy Cyclin D1 Epidermal growth factor receptors Evidence-based medicine Female Fractionation Head Head & neck cancer Head and neck cancer Head and Neck Neoplasms - diagnosis Head and Neck Neoplasms - mortality Head and Neck Neoplasms - radiotherapy Health aspects Health risks Histology Human papillomavirus Humans Kinases Larynx Male Medical research Medicine Metastasis Middle Aged Neoplasia Neoplasm Grading Neoplasms Nucleoside-diphosphate kinase Oncology Oral cancer Oral cavity Oropharynx p53 Protein Paraffin Pathology Patients Phosphatase Postoperative Period Prognosis Prostate Prostate cancer PTEN Phosphohydrolase - metabolism PTEN protein Radiation therapy Radiotherapy Risk Factors Senescence Signal transduction Squamous cell carcinoma Thyroid Thyroid cancer Thyroid gland Treatment Outcome Tumor proteins Tumor suppressor genes Tumorigenesis Tumors
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