Variants in exon 11 of MEF2A gene and coronary artery disease: evidence from a case-control study, systematic review, and meta-analysis

Coronary artery disease (CAD) is the most common heart disease worldwide. Association of CAD with variants in the myocyte enhancer factor 2A (MEF2A) gene, the first identified CAD-causing gene, has attracted special attention but the results are controversial. We aimed to evaluate this genetic assoc...

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Veröffentlicht in:	PloS one 2012-02, Vol.7 (2), p.e31406
Hauptverfasser:	Liu, Yan, Niu, Wenquan, Wu, Zhijun, Su, Xiuxiu, Chen, Qiujin, Lu, Lin, Jin, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alleles Analysis Base Pairing - genetics Biology Cardiology Cardiovascular disease Case-Control Studies Coronary artery Coronary artery disease Coronary Artery Disease - genetics Coronary heart disease Coronary vessels Disease control Exons - genetics Gene deletion Gene polymorphism Genes Genetic diversity Genetic Heterogeneity Genetic polymorphisms Genetic Predisposition to Disease Genetic variance Genetic Variation Genomes Genomics Heart diseases Hospitals Humans Hypotheses MADS Domain Proteins - genetics Medical imaging Medical research Medicine MEF2 Transcription Factors Meta-analysis Middle Aged Mutation Myocardial Infarction - genetics Myogenic Regulatory Factors - genetics Patients Polyglutamine Polymorphism Polymorphism, Genetic Population Precision medicine Risk Factors Sequence Analysis, DNA Sequence Deletion - genetics Single-nucleotide polymorphism Studies Systematic review Trinucleotide Repeat Expansion - genetics Trinucleotide repeats
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