In vivo diagnostic imaging using micro-CT: sequential and comparative evaluation of rodent models for hepatic/brain ischemia and stroke

There is an increasing need for animal disease models for pathophysiological research and efficient drug screening. However, one of the technical barriers to the effective use of the models is the difficulty of non-invasive and sequential monitoring of the same animals. Micro-CT is a powerful tool f...

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Veröffentlicht in:	PloS one 2012-02, Vol.7 (2), p.e32342-e32342
Hauptverfasser:	Hayasaka, Naoto, Nagai, Nobuo, Kawao, Naoyuki, Niwa, Atsuko, Yoshioka, Yoshichika, Mori, Yuki, Shigeta, Hiroshi, Kashiwagi, Nobuo, Miyazawa, Masaaki, Satou, Takao, Higashino, Hideaki, Matsuo, Osamu, Murakami, Takamichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy & physiology Animal diseases Animal models Animal tissues Animals Biology Blood Pressure Brain Brain - pathology Brain damage Brain Ischemia - pathology Brain research CAT scans Cerebral infarction Comparative analysis Computed tomography Contrast Media - pharmacology Diagnostic imaging Diagnostic software Diagnostic systems Disease Disease Models, Animal Drug screening Genetic engineering Histology Hypertension Hypertensive Encephalopathy Image acquisition Image contrast Immunology Infarction Ischemia Ischemia - pathology Laboratories Lesions Liver Liver - pathology Magnetic resonance imaging Male Medical diagnosis Medical imaging Medical research Medicine Mice Mice, Inbred BALB C Neuroimaging Neurosciences NMR Nuclear magnetic resonance Organs Oxidative stress Pathology Permeability Physiology Rats Rodentia Rodents Stroke Stroke - pathology Surgery Surgical instruments Technology application Thrombosis Time Factors Traumatic brain injury Veins & arteries X-Ray Microtomography - methods
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