Overexpression of ZEB2 in peritumoral liver tissue correlates with favorable survival after curative resection of hepatocellular carcinoma

ZEB2 has been suggested to mediate EMT and disease aggressiveness in several types of human cancers. However, the expression patterns of ZEB2 in hepatocellular carcinoma (HCC) and its effect on prognosis of HCC patients treated with hepatectomy are unclear. In this study, the methods of tissue micro...

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Veröffentlicht in:	PloS one 2012-02, Vol.7 (2), p.e32838-e32838
Hauptverfasser:	Cai, Mu-Yan, Luo, Rong-Zhen, Chen, Jie-Wei, Pei, Xiao-Qing, Lu, Jia-Bin, Hou, Jing-Hui, Yun, Jing-Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Biology Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - therapy Cell cycle Committees Correlation Cytoplasm - metabolism Data processing Epithelial-Mesenchymal Transition Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Hazards Hepatectomy Hepatitis Hepatocellular carcinoma Homeodomain Proteins - biosynthesis Humans Immunohistochemistry Immunohistochemistry - methods Laboratories Liver Liver - metabolism Liver cancer Liver diseases Liver Neoplasms - metabolism Liver Neoplasms - therapy Male Medical ethics Medical prognosis Medical research Medicine Metastasis Middle Aged Multivariate Analysis Oligonucleotide Array Sequence Analysis Oncology Pancreatic cancer Pathology Patients Prognosis Proteins Regression analysis Regression models Repressor Proteins - biosynthesis ROC Curve Rodents Surgery Survival Tumorigenesis Tumors Zinc Finger E-box Binding Homeobox 2
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