S phase entry of neural progenitor cells correlates with increased blood flow in the young subventricular zone

The postnatal subventricular zone (SVZ) contains proliferating neural progenitor cells in close proximity to blood vessels. Insults and drug treatments acutely stimulate cell proliferation in the SVZ, which was assessed by labeling cells entering S phase. Although G1-to-S progression is metabolicall...

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Veröffentlicht in:	PloS one 2012-02, Vol.7 (2), p.e31960-e31960
Hauptverfasser:	Lacar, Benjamin, Herman, Peter, Hartman, Nathaniel W, Hyder, Fahmeed, Bordey, Angelique
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Biology Blood Blood flow Blood vessels Brain Brain research Brain slice preparation Capillaries Cell cycle Cell growth Cell Proliferation Cells (biology) Communications networks Coupling Doppler effect Energy resources Epidermal growth factor Epidermal growth factors Fibroblast growth factor Fibroblast growth factor 2 Fibroblast growth factors Growth factors Hemodynamics Hemopoiesis Injection Lateral Ventricles - blood supply Lateral Ventricles - cytology Medicine Mice Neostriatum Nervous system Neural stem cells Neural Stem Cells - cytology Neurosciences Neurosurgery Nutrient cycles Perfusion Physiology Regional Blood Flow - physiology Rodents S Phase Smooth muscle Spinal cord Stem cells Substrates Subventricular zone Thromboxane A2 Ventricle Ventricles (cerebral)
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