Role of mesenchymal stem cells on cornea wound healing induced by acute alkali burn

The aim of this study was to investigate the effects of subconjunctivally administered mesenchymal stem cells (MSCs) on corneal wound healing in the acute stage of an alkali burn. A corneal alkali burn model was generated by placing a piece of 3-mm diameter filter paper soaked in NaOH on the right e...

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Veröffentlicht in:	PloS one 2012-02, Vol.7 (2), p.e30842
Hauptverfasser:	Yao, Lin, Li, Zhan-rong, Su, Wen-ru, Li, Yong-ping, Lin, Miao-li, Zhang, Wen-xin, Liu, Yi, Wan, Qian, Liang, Dan
Format:	Artikel
Sprache:	eng
Schlagworte:	Addition polymerization Alkalies Analysis Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Antigens Biology Bone marrow Burns Burns, Chemical - drug therapy Burns, Chemical - pathology Burns, Chemical - therapy Cell Movement - drug effects Cornea Cornea - drug effects Cornea - pathology Corneal Neovascularization - drug therapy Corneal Neovascularization - pathology Enzyme-linked immunosorbent assay Epithelium Epithelium, Corneal - pathology Eye Female Filter paper Flow cytometry Gene expression Immunofluorescence Immunoglobulins Inflammation Injection Injuries Laboratories Lymphocytes Macrophage inflammatory protein Macrophage inflammatory protein 1 Macrophages Medicine Mesenchymal Stem Cell Transplantation Mesenchymal stem cells Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Mesenchyme Monocyte chemoattractant protein 1 Neovascularization Penicillin Phosphates Polymerase chain reaction Rats Rats, Sprague-Dawley Real time RNA Rodents Skin & tissue grafts Stem cells Tumor necrosis factor-α Vascular endothelial growth factor Vascularization Wound healing Wound Healing - drug effects
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