Use of a molecular diagnostic test in AFB smear positive tuberculosis suspects greatly reduces time to detection of multidrug resistant tuberculosis

The WHO has recommended the implementation of rapid diagnostic tests to detect and help combat M/XDR tuberculosis (TB). There are limited data on the performance and impact of these tests in field settings. The performance of the commercially available Genotype MTBDRplus molecular assay was compared...

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Veröffentlicht in:	PloS one 2012-02, Vol.7 (2), p.e31563-e31563
Hauptverfasser:	Tukvadze, Nestani, Kempker, Russell R, Kalandadze, Iagor, Kurbatova, Ekaterina, Leonard, Michael K, Apsindzelashvili, Rusudan, Bablishvili, Nino, Kipiani, Maia, Blumberg, Henry M
Format:	Artikel
Sprache:	eng
Schlagworte:	Air bases Antitubercular agents Antitubercular Agents - pharmacology Assaying Biology Chemotherapy Clinical outcomes Codons Diagnostic systems Diagnostic tests Disease control Drug resistance Genotype & phenotype Georgia Hepatitis Humans Infectious diseases Isoniazid Isoniazid - pharmacology Laboratories Lung diseases Medical diagnosis Medical screening Medicine Microscopy Molecular Diagnostic Techniques - methods Multidrug resistance Multidrug resistant organisms Mutation Mycobacterium tuberculosis Reproducibility of Results Rifampin RpoB protein Smear Sputum Sputum - microbiology Tuberculosis Tuberculosis, Multidrug-Resistant - diagnosis Tuberculosis, Multidrug-Resistant - genetics
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