Mutational robustness of gene regulatory networks

Mutational robustness of gene regulatory networks refers to their ability to generate constant biological output upon mutations that change network structure. Such networks contain regulatory interactions (transcription factor-target gene interactions) but often also protein-protein interactions bet...

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Veröffentlicht in:	PloS one 2012-01, Vol.7 (1), p.e30591-e30591
Hauptverfasser:	van Dijk, Aalt D J, van Mourik, Simon, van Ham, Roeland C H J
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Arabidopsis - genetics autoregulation Binding sites Bioinformatics Biological effects Biological evolution Biology chip-seq Computational Biology Computer applications Conservation Deoxyribonucleic acid dimerization DNA DNA binding proteins evolution Evolution, Molecular Evolutionary conservation evolvability expression Gene expression Gene Regulatory Networks - genetics Genes Genetic aspects Genetic research Genomes Humans mechanisms Mutation Networks noise Ordinary differential equations Plant sciences Protein interaction Protein-protein interactions Proteins Robustness (mathematics) Studies Transcription (Genetics) transcription factor-binding Transcription factors Transcription Factors - metabolism Transcriptome - genetics yeast
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