Proteomes and signalling pathways of antler stem cells

As the only known example of complete organ regeneration in mammals, deer antler in the growing or velvet phase is of major interest in developmental biology. This regeneration event initiates from self-renewing antler stem cells that exhibit pluripotency. At present, it remains unclear how the acti...

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Veröffentlicht in:	PloS one 2012-01, Vol.7 (1), p.e30026-e30026
Hauptverfasser:	Li, Chunyi, Harper, Anne, Puddick, Jonathan, Wang, Wenying, McMahon, Chris
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Acids AKT protein Animals Antlers Antlers - cytology Antlers - metabolism Biology Blotting, Western Cancer Cell cycle Cells, Cultured Cervidae Cloning Deer Deer - metabolism Developmental biology DNA binding proteins Electrophoresis, Gel, Two-Dimensional Embryo cells Embryonic stem cells Galectin 1 - metabolism Gene expression Homeodomain Proteins - metabolism Male MAP kinase Models, Biological Muscles Myc protein Nervous system Neutrophils Oct-4 protein Octamer Transcription Factor-3 - metabolism Periosteum Periosteum - cytology Periosteum - metabolism Pluripotency Proteins Proteome - metabolism Proteomics Proteomics - methods Proto-Oncogene Proteins c-myc - metabolism Regeneration S100 Proteins - metabolism Signal Transduction Signaling Somatic cells SOXB1 Transcription Factors - metabolism Stem cells Stem Cells - metabolism Tissues Transcription factors Trends
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