Uterine dysfunction in biglycan and decorin deficient mice leads to dystocia during parturition

Cesarean birth rates are rising. Uterine dysfunction, the exact mechanism of which is unknown, is a common indication for Cesarean delivery. Biglycan and decorin are two small leucine-rich proteoglycans expressed in the extracellular matrix of reproductive tissues and muscle. Mice deficient in bigly...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2012-01, Vol.7 (1), p.e29627
Hauptverfasser:	Wu, Zhiping, Aron, Abraham W, Macksoud, Elyse E, Iozzo, Renato V, Hai, Chi-Ming, Lechner, Beatrice E
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Analysis Animal models Animal tissues Animals Arthritis Biglycan - deficiency Biglycan - metabolism Biology Biomechanical Phenomena - drug effects Birth Cesarean section Collagen Connective tissues Coronary vessels Decorin Decorin - deficiency Decorin - metabolism Dystocia Dystocia - pathology Dystocia - physiopathology Dystrophy Ehlers-Danlos syndrome Embryos Enterococcus faecium Extracellular matrix Female Gene mutation Genotypes Immunohistochemistry In vivo methods and tests Labor Leucine Male Medical schools Medicine Mice Mice, Inbred C3H Mice, Knockout Model testing Morphology Muscle contraction Muscles Muscular dystrophy Mutation Osteoporosis Oxytocin Oxytocin - pharmacology Parturition Parturition - drug effects Parturition - physiology Pediatrics Pregnancy Premature birth Proteoglycans Rodents Transforming Growth Factor beta - metabolism Uterine Contraction - drug effects Uterine Contraction - physiology Uterus Uterus - drug effects Uterus - pathology Uterus - physiopathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!