GABA expression and regulation by sensory experience in the developing visual system

The developing retinotectal system of the Xenopus laevis tadpole is a model of choice for studying visual experience-dependent circuit maturation in the intact animal. The neurotransmitter gamma-aminobutyric acid (GABA) has been shown to play a critical role in the formation of sensory circuits in t...

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Veröffentlicht in:	PloS one 2012-01, Vol.7 (1), p.e29086-e29086
Hauptverfasser:	Miraucourt, Loïs S, Silva, Jorge Santos da, Burgos, Kasandra, Li, Jianli, Abe, Hikari, Ruthazer, Edward S, Cline, Hollis T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptability Analysis Anatomy Animals Biology Brain Brain - growth & development Brain - metabolism Brain architecture Brain research Brain-derived neurotrophic factor Circuits Developmental stages Enzyme-Linked Immunosorbent Assay Experiments Fluorescent Antibody Technique GABA GABAergic Neurons - metabolism gamma-Aminobutyric Acid - metabolism Homeostasis Immunoreactivity Innervation Laboratories Larva - cytology Larva - metabolism Nervous system Neurons Photic Stimulation Physiology Quantitative analysis Retina Retina - cytology Retina - growth & development Retina - metabolism Sensation - physiology Spatial distribution Superior Colliculi - growth & development Superior Colliculi - metabolism Superior colliculus Tectum Tumor necrosis factor-TNF Visual observation Visual pathways Visual Pathways - cytology Visual Pathways - growth & development Visual Pathways - metabolism Visual stimuli Visual system Xenopus laevis Xenopus laevis - growth & development Xenopus laevis - metabolism γ-Aminobutyric acid
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