Organically modified silica nanoparticles are biocompatible and can be targeted to neurons in vivo

The application of nanotechnology in biological research is beginning to have a major impact leading to the development of new types of tools for human health. One focus of nanobiotechnology is the development of nanoparticle-based formulations for use in drug or gene delivery systems. However most...

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Veröffentlicht in:	PloS one 2012-01, Vol.7 (1), p.e29424
Hauptverfasser:	Barandeh, Farda, Nguyen, Phuong-Lan, Kumar, Rajiv, Iacobucci, Gary J, Kuznicki, Michelle L, Kosterman, Andrew, Bergey, Earl J, Prasad, Paras N, Gunawardena, Shermali
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Alzheimer's disease Alzheimers disease Animals Biocompatibility Biological research Biology Blood-brain barrier Blood-Brain Barrier - drug effects Blood-Brain Barrier - metabolism Brain Caenorhabditis elegans Cancer Cell body Cells, Cultured Cytoplasm Drosophila Drosophila - drug effects Drosophila - embryology Drosophila - growth & development Drug delivery systems Drug Delivery Systems - methods Embryo, Nonmammalian Female Formulations Gene therapy Gene transfer In vivo methods and tests Insects Male Materials Science Materials Testing - methods Medicine Motor neurone disease Mutation Nanoparticles Nanoparticles - administration & dosage Nanoparticles - adverse effects Nanoparticles - chemistry Nanotechnology Neurons Neurons - cytology Neurons - drug effects Neurons - metabolism Organisms Photodynamic therapy Photonics Primary Cell Culture Proteins Quantum dots Roads & highways Senescence Silica Silicon dioxide Silicon Dioxide - administration & dosage Silicon Dioxide - adverse effects Silicon Dioxide - chemistry Silicon Dioxide - pharmacology Siloxanes - administration & dosage Siloxanes - adverse effects Siloxanes - chemistry Siloxanes - pharmacology Studies Toxicity Traffic congestion Viability
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