Challenge of pigs with classical swine fever viruses after C-strain vaccination reveals remarkably rapid protection and insights into early immunity

Pre-emptive culling is becoming increasingly questioned as a means of controlling animal diseases, including classical swine fever (CSF). This has prompted discussions on the use of emergency vaccination to control future CSF outbreaks in domestic pigs. Despite a long history of safe use in endemic...

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Veröffentlicht in:	PloS one 2012-01, Vol.7 (1), p.e29310-e29310
Hauptverfasser:	Graham, Simon P, Everett, Helen E, Haines, Felicity J, Johns, Helen L, Sosan, Olubukola A, Salguero, Francisco J, Clifford, Derek J, Steinbach, Falko, Drew, Trevor W, Crooke, Helen R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal diseases Animal health Animals Antibodies, Neutralizing - immunology Antiviral agents Biology Classical Swine Fever - prevention & control Classical Swine Fever - transmission Classical swine fever virus - immunology Classical swine fever virus - pathogenicity Culling Disease transmission Equivalence Fever Genotype & phenotype Genotypes Glycoproteins Hog cholera Hogs Immunity Infections Interferon-gamma - metabolism Laboratories Livestock Lymphocytes T Male Outbreaks Phylogenetics Stability Strains (organisms) Suidae Sus scrofa Swine Swine - immunology Swine - virology T cells T-Lymphocytes - immunology T-Lymphocytes - virology Time Factors Vaccination Vaccination - methods Vaccines Veterinary Science Virology Viruses Wildlife conservation γ-Interferon
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