Matrix metalloproteinase 1: role in sarcoma biology

In carcinomas stromal cells participate in cancer progression by producing proteases such as MMPs. The expression MMP1 is a prognostic factor in human chondrosarcoma, however the role in tumor progression is unknown. Laser capture microdissection and In Situ hybridization were used to determine cell...

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Veröffentlicht in:	PloS one 2010-12, Vol.5 (12), p.e14250-e14250
Hauptverfasser:	Jawad, Muhammad Umar, Garamszegi, Nandor, Garamszegi, Susanna P, Correa-Medina, Mayrin, Diez, Juan A, Wen, Rong, Scully, Sean P
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Angiogenesis Animals Biological effects Biology Biopsy Bone cancer Breast cancer Cancer Cancer metastasis Carcinoma Cell Biology Cell Biology/Extra-Cellular Matrix Cell Proliferation Chondrosarcoma Clinical trials Development and progression Diabetes Disease Progression Fibroblasts Gene expression Gene Expression Regulation, Enzymologic Gene Silencing Hospitals Humans Hybridization In Situ Hybridization, Fluorescence Labeling Lasers Lungs Matrix metalloproteinase Matrix Metalloproteinase 1 - metabolism Matrix metalloproteinases Medical research Medicine Metalloproteinase Metastases Metastasis Mice Mice, SCID Models, Biological Neoplasm Invasiveness Neoplasm Transplantation Neovascularization Neovascularization, Pathologic Oncology/Sarcomas Orthopedics Prognosis Proteases Ribonucleic acid RNA Sarcoma Sarcoma - enzymology Stromal cells Studies Tumor cells Vascular endothelial growth factor Vascularization
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