Comment on "genomic hypomethylation in the human germline associates with selective structural mutability in the human genome"

Based on an analysis of DNA methylation patterns in human sperm, Li et al. recently reported a significant relationship between CNVs and hypomethylation in the male germline [9], leading to the suggestion that DNA hypomethylation plays a causative role in the generation of structural variation. Furt...

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Veröffentlicht in:	PLoS genetics 2013-02, Vol.9 (2), p.e1003332-e1003332
Hauptverfasser:	Watson, Corey T, Garg, Paras, Sharp, Andrew J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology Deoxyribonucleic acid DNA DNA Copy Number Variations DNA Methylation Gene mutations Genetic engineering Genetics Genome, Human Genomes Genomics Germ Cells Humans Methylation Mutation Rate Satellites Sperm Viewpoints
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