The stringent response and cell cycle arrest in Escherichia coli

The bacterial stringent response, triggered by nutritional deprivation, causes an accumulation of the signaling nucleotides pppGpp and ppGpp. We characterize the replication arrest that occurs during the stringent response in Escherichia coli. Wild type cells undergo a RelA-dependent arrest after tr...

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Veröffentlicht in:	PLoS genetics 2008-12, Vol.4 (12), p.e1000300-e1000300
Hauptverfasser:	Ferullo, Daniel J, Lovett, Susan T
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Outer Membrane Proteins - genetics Bacterial Outer Membrane Proteins - metabolism Cell Cycle Chromosome Segregation Chromosomes Chromosomes, Bacterial - genetics DNA methylation DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Escherichia coli Escherichia coli - cytology Escherichia coli - genetics Escherichia coli - metabolism Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Genetics and Genomics/Chromosome Biology Microbiology Microbiology/Microbial Growth and Development Microbiology/Microbial Physiology and Metabolism Mutation Origin Recognition Complex - genetics Origin Recognition Complex - metabolism Replication Origin Site-Specific DNA-Methyltransferase (Adenine-Specific) - genetics Site-Specific DNA-Methyltransferase (Adenine-Specific) - metabolism
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