Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation

Embryonic stem (ES) cells are pluripotent cells derived from the inner cell mass of the mammalian blastocyst. Cellular differentiation entails loss of pluripotency and gain of lineage-specific characteristics. However, the molecular controls that govern the differentiation process remain poorly unde...

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Veröffentlicht in:	PLoS genetics 2009-08, Vol.5 (8), p.e1000620-e1000620
Hauptverfasser:	Ciaudo, Constance, Servant, Nicolas, Cognat, Valérie, Sarazin, Alexis, Kieffer, Emmanuelle, Viville, Stéphane, Colot, Vincent, Barillot, Emmanuel, Heard, Edith, Voinnet, Olivier
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Binding sites Biochemistry, Molecular Biology Cell adhesion & migration Cell Differentiation Cell Line Cellular biology Developmental Biology/Cell Differentiation Developmental Biology/Germ Cells Developmental Biology/Stem Cells Embryonic development Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Embryos Epigenetics Female Gene Expression Genetics and Genomics/Bioinformatics Germ Cells - cytology Germ Cells - metabolism Humans Life Sciences Male Mice MicroRNAs - genetics MicroRNAs - metabolism Molecular Sequence Data Phase transitions RNA Sex Characteristics Skin cancer Stem cells Studies
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