Genome-wide analysis of heteroduplex DNA in mismatch repair-deficient yeast cells reveals novel properties of meiotic recombination pathways

Meiotic DNA double-strand breaks (DSBs) initiate crossover (CO) recombination, which is necessary for accurate chromosome segregation, but DSBs may also repair as non-crossovers (NCOs). Multiple recombination pathways with specific intermediates are expected to lead to COs and NCOs. We revisited the...

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Veröffentlicht in:	PLoS genetics 2011-09, Vol.7 (9), p.e1002305-e1002305
Hauptverfasser:	Martini, Emmanuelle, Borde, Valérie, Legendre, Matthieu, Audic, Stéphane, Regnault, Béatrice, Soubigou, Guillaume, Dujon, Bernard, Llorente, Bertrand
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology Cell division Chromatids - genetics Chromosome Segregation Chromosomes Crossing over (Genetics) Crossing Over, Genetic Deoxyribonucleic acid DNA DNA Breaks, Double-Stranded DNA damage DNA Mismatch Repair - genetics DNA repair DNA Repair - genetics DNA, Cruciform - genetics Environmental Sciences Genetic aspects Genetic recombination Genome-Wide Association Study Life Sciences Meiosis Meiosis - genetics MutS Homolog 2 Protein - genetics Nucleic Acid Heteroduplexes - genetics Physiological aspects Proteins Recombination, Genetic Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Sister Chromatid Exchange Yeast Yeast fungi
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