Competitive repair by naturally dispersed repetitive DNA during non-allelic homologous recombination

Genome rearrangements often result from non-allelic homologous recombination (NAHR) between repetitive DNA elements dispersed throughout the genome. Here we systematically analyze NAHR between Ty retrotransposons using a genome-wide approach that exploits unique features of Saccharomyces cerevisiae...

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Veröffentlicht in:	PLoS Genetics 2010-12, Vol.6 (12), p.e1001228-e1001228
Hauptverfasser:	Hoang, Margaret L, Tan, Frederick J, Lai, David C, Celniker, Sue E, Hoskins, Roger A, Dunham, Maitreya J, Zheng, Yixian, Koshland, Douglas
Format:	Artikel
Sprache:	eng
Schlagworte:	60 ABUNDANCE BIOLOGICAL PATHWAYS Brewer's yeast Competition Deoxyribonucleic acid DNA DNA Breaks, Double-Stranded DNA damage DNA Repair DNA Transposable Elements Genetic aspects Genetic recombination Genetics Genome, Fungal Molecular Biology/Chromosome Structure Molecular Biology/DNA Repair Molecular Biology/Recombination NEOPLASMS RECOMBINATION Recombination, Genetic REPAIR Repetitive Sequences, Nucleic Acid SACCHAROMYCES Saccharomyces - genetics Saccharomyces bayanus SACCHAROMYCES CEREVISIAE Saccharomyces cerevisiae - genetics Yeast
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