Diverse CRISPRs evolving in human microbiomes

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) loci, together with cas (CRISPR-associated) genes, form the CRISPR/Cas adaptive immune system, a primary defense strategy that eubacteria and archaea mobilize against foreign nucleic acids, including phages and conjugative plasmids....

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Veröffentlicht in:	PLoS genetics 2012-06, Vol.8 (6), p.e1002441-e1002441
Hauptverfasser:	Rho, Mina, Wu, Yu-Wei, Tang, Haixu, Doak, Thomas G, Ye, Yuzhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Archaea - genetics Arrays Bacteria - genetics Bacteria - virology Bacteriophages - genetics Base Sequence Biology DNA, Intergenic - genetics Evolution, Molecular Genetic aspects Genetic engineering Genome, Bacterial Genomes Humans Identification and classification Inverted Repeat Sequences - genetics Metagenome - genetics Metagenomics Microbiology Microorganisms Molecular Sequence Data Nucleotide sequence Plasmids Plasmids - genetics Sequence Analysis, DNA Streptococcus - genetics Streptococcus - virology
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